ITI214 free base
目录号: A21947
picomolar PDE1 inhibitor
ITI-214(游离碱)是一种皮克摩尔级的PDE1抑制剂,具有针对其他PDE家族成员以及一系列酶、受体、转运体和离子通道的极佳选择性,展示出强大的PDE1抑制活性(Ki = 58 pM)。
Discription | ITI-214 (free base) is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM). | ||
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目录号 | A21947 |
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分子式 | C29H26FN7O |
分子量 | 507.56 |
CAS号 | 1160521-50-5 |
SMILES | O=C(C1=C(NC2=CC=CC=C2)N(CC3=CC=C(C4=NC(F)=CC=C4)C=C3)N=C1N56)N(C)C5=N[C@@]7([H])[C@]6([H])CCC7 |
其他名称 | ITI-214, ITI 214 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2