IWP-2
目录号: A12707
Wnt 抑制剂
IWP-2 是 Porcn 功能的失活剂和 Wnt 产生的抑制剂,能够阻断 beta-catenin 的积累。Wnt/beta-catenin(“典型”)途径维持使干细胞保持多能性的转录程序。
Discription | IWP-2 is an inactivator of Porcn function and inhibitor of Wnt production, and blocks beta-catenin accumulation. Wnt/b-catenin ('canonical') pathway maintains transcriptional programs that enable stem cells to remain multipotent. | |||||
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Targets |
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Cell Research |
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目录号 | A12707 |
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分子式 | C22H18N4O2S3 |
分子量 | 466.6 |
CAS号 | 686770-61-6 |
SMILES | CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4 |
其他名称 | IWP 2,IWP2 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Insoluble | |
Water | Insoluble | ||
Ethanol | DMF: 24mg/mL (51.44 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.43 mL | 107.16 mL | 214.32 mL |
0.5 mM | 4.29 mL | 21.43 mL | 42.86 mL |
1 mM | 2.14 mL | 10.72 mL | 21.43 mL |
5 mM | 0.43 mL | 2.14 mL | 4.29 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2