IWP-O1
目录号: A16846
PORCN 抑制剂
IWP-O1 是一种 porcn 抑制剂，在 Wnt 信号传导的培养细胞报告检测中具有 80 pM 的 EC50 值，并且能有效抑制 HeLa 细胞中 Dvl2/3 的磷酸化。
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生物活性
| Discription | IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells. |
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产品信息
| 目录号 | A16846 |
|---|---|
| 分子式 | C26H20N6O |
| 分子量 | 432.48 |
| CAS号 | 2074607-48-8 |
| SMILES | O=C(NC1=NC=C(C2=CC=CC=C2)C=C1)CN3N=NC(C4=CC=NC=C4)=C3C5=CC=CC=C5 |
| 其他名称 | IWPO1, IWP O1 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 79 mg/mL (182.66 mM) | |
| Water | Insoluble | ||
| Ethanol | 79 mg/mL (182.66 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.12 mL | 115.61 mL | 231.22 mL |
| 0.5 mM | 4.62 mL | 23.12 mL | 46.24 mL |
| 1 mM | 2.31 mL | 11.56 mL | 23.12 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.62 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 2074607-48-8 | 2074607-48-8 供应商 | 2074607-48-8 花费 | 2074607-48-8 生产商 | 订购 2074607-48-8 | 2074607-48-8 代理商