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IWP-O1

产品详情

生物活性

IWP-O1是一种porcn抑制剂，在Wnt信号的培养细胞报告基因分析中的EC50值为80 pM，可有效抑制HeLa细胞中Dvl2/3的磷酸化。

溶解度 *

In vitro	DMSO	79 mg/mL (182.66 mM)
	Water	Insoluble
	Ethanol	79 mg/mL (182.66 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.12 mL	115.61 mL	231.22 mL
0.5 mM	4.62 mL	23.12 mL	46.24 mL
1 mM	2.31 mL	11.56 mL	23.12 mL
5 mM	0.46 mL	2.31 mL	4.62 mL

*The above data is based on the productmolecular weight 432.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16846
作用机制	Inhibitor (抑制剂)
M. Wt	432.48
Formula	C26H20N6O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2074607-48-8
Synonyms	IWPO1, IWP O1
SMILES	O=C(NC1=NC=C(C2=CC=CC=C2)C=C1)CN3N=NC(C4=CC=NC=C4)=C3C5=CC=CC=C5