Ixazomib citrate (MLN9708)
目录号: A18017
20S proteasome 抑制剂
Ixazomib citrate (MLN9708) 是一种可逆的抑制剂,针对20S蛋白酶体的类胰蛋白酶β5活性位点,具有3.4 nM的IC50和0.93 nM的Ki。
Discription | Ixazomib citrate (MLN9708) is a reversible inhibitor of the chymotrypsin-like proteolytic β5 site of the 20S proteasome with an IC50 of 3.4 nM and a Ki of 0.93 nM. |
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目录号 | A18017 |
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分子式 | C20H23BCl2N2O9 |
分子量 | 517.12 |
CAS号 | 1239908-20-3 |
SMILES | O=C(O)CC1(CC(O)=O)OB([C@@H](NC(CNC(C2=CC(Cl)=CC=C2Cl)=O)=O)CC(C)C)OC1=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2