JAK1-IN-3
目录号: A19251
JAK1 inhibitor
JAK1-IN-3 是一种选择性的 JAK1 抑制剂,其 IC50 为 73 nM,对 JAK2 的抑制作用较弱,并且对 JAK3 几乎没有抑制作用(IC50 分别为 >14.7, >30 μM)。
Discription | JAK1-IN-3 is a selective JAK1 inhibitor, with an IC50 of 73 nM, weakly inhibits JAK2, and shows little inhibition on JAK3 (IC50, >14.7, >30 μM, respectively). | |||||
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Cell Research |
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目录号 | A19251 |
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分子式 | C25H31N9O2 |
分子量 | 489.57 |
CAS号 | 2091134-68-6 |
SMILES | C[C@@H](N1CCN(C)CC1)C(NC2=C3C(C(C4=NC(NC5=CN(C)N=C5OC)=NC=C4)=CN3)=CC=C2)=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2