JAK1-IN-4

Name: JAK1-IN-4
SKU: A18821
Price: 2205 CNY
Rating: 5 (288 reviews)

目录号: A18821

JAK1 抑制剂

JAK1-IN-4 是一种高效且选择性的 JAK1 抑制剂，其 IC50 分别为 85 nM、12.8 μM 和 >30 μM，针对 JAK1、JAK2 和 JAK3。JAK1-IN-4 在 NCI-H 1975 细胞中抑制 STAT3 磷酸化（IC50 为 227 nM）。

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规格	价格	库存
1mg	¥2,205.00	现货
5mg	¥4,760.00	现货
10mg	¥7,665.00	现货
25mg	¥11,655.00	现货
50mg	¥15,225.00	现货
100mg	¥19,565.00	现货
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Data Sheet

SDS

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生物活性

Discription

JAK1-IN-4 is a potent and selective JAK1 inhibitor, with IC50s of 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively. JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM).

Targets

Target	Value

产品信息

目录号	A18821
分子式	C26H32FN9O2
分子量	521.59
CAS号	2091134-35-7
SMILES	O=C(NC1=CC=CC2=C1NC=C2C3=C(C=NC(NC4=CN(N=C4OC)C)=N3)F)[C@H](N5CCN([C@@H](C5)C)C)C
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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