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JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.3 mL | 106.48 mL | 212.97 mL |
| 0.5 mM | 4.26 mL | 21.3 mL | 42.59 mL |
| 1 mM | 2.13 mL | 10.65 mL | 21.3 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.26 mL |
*The above data is based on the productmolecular weight 469.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12182 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 469.56 |
| Formula | C23H27N5O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1438284-00-4 |
| SMILES | CC(C=NC(NC1=CC=C(N2CCOCC2)C=C1)=N3)=C3C(O4)=CC5=C4CCN(S(=O)(C)=O)C5 |
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