JAK3 covalent inhibitor-1
目录号: A18926
JAK3 covalent 抑制剂
JAK3 covalent inhibitor-1 是一种强效且选择性的 janus kinase 3 (JAK3) 共价抑制剂,其 IC50 为 11 nM,并且相对于其他 JAKs 显示出 246 倍的选择性。
Discription | JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs. | ||
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目录号 | A18926 |
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分子式 | C22H17FN6O2S |
分子量 | 448.47 |
CAS号 | 2300106-50-5 |
SMILES | O=S(N[C@H](C[C@@H]1NC#N)C(C1=C2)=CC=C2C3=C4C(NC=C4)=NC=N3)(C5=CC=CC(F)=C5)=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2