产品详情
JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.3 mL | 111.49 mL | 222.98 mL |
0.5 mM | 4.46 mL | 22.3 mL | 44.6 mL |
1 mM | 2.23 mL | 11.15 mL | 22.3 mL |
5 mM | 0.45 mL | 2.23 mL | 4.46 mL |
*The above data is based on the productmolecular weight 448.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A18926 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 448.47 |
Formula | C22H17FN6O2S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 2300106-50-5 |
Synonyms | 0 |
SMILES | O=S(N[C@H](C[C@@H]1NC#N)C(C1=C2)=CC=C2C3=C4C(NC=C4)=NC=N3)(C5=CC=CC(F)=C5)=O |
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