JG-98

Name: JG-98
SKU: A18734
Price: 665 CNY
Rating: 5 (3 reviews)

目录号: A18734

Hsp70 抑制剂

3 篇发表文献

JG-98 是一种选择性的热休克蛋白70（Hsp70）调节剂，它紧密结合于 Hsp70 上的一个保守位点，并破坏 Hsp70-Bag3 之间的相互作用。JG-98 表现出抗癌活性，影响癌细胞和肿瘤相关巨噬细胞。

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Grouped product items
规格	价格	库存
1mg	¥665.00	现货
5mg	¥1,330.00	现货
10mg	¥2,135.00	现货
25mg	¥3,570.00	现货
50mg	¥5,040.00	现货
100mg	¥6,615.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用JG-98发表的3篇文献

Mizuho Nosaka, .et al. , Sci Rep, 2023, Dec 16;13(1):22416 PMID: 38104135

Siu Hong Dexter Wong, .et al. , Sci Adv, 2023, Jul 7;9(27):eadg9593 PMID: 37418519

Shivani Patel, .et al. , iScience, 2022, Apr 22;25(5):104282 PMID: 35573186

生物活性

Discription

JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A18734
分子式	C24H21Cl2N3OS3
分子量	534.54
CAS号	1456551-16-8
SMILES	CN1/C(SC2=CC(Cl)=CC=C12)=C3S/C(N(CC)C\3=O)=C\C4=[N+](C=CS4)CC5=CC=CC=C5.[Cl-]
其他名称	JG98, JG 98
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	7 mg/mL (13.09 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.71 mL	93.54 mL	187.08 mL
0.5 mM	3.74 mL	18.71 mL	37.42 mL
1 mM	1.87 mL	9.35 mL	18.71 mL
5 mM	0.37 mL	1.87 mL	3.74 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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