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JH-II-127

目录号: A15777
LRRK2 抑制剂
JH-II-127 是一种高效、选择性强且能穿透血脑屏障的 LRRK2 抑制剂,其 IC50 分别为 6.6 nM、2.2 nM、47.7 nM,针对 LRRK2-野生型LRRK2-G2019SLRRK2-A2016T
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规格 价格 库存 数量
1mg
¥280.00
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5mg
¥700.00
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10mg
¥1,155.00
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25mg
¥2,030.00
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50mg
¥3,290.00
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100mg
¥4,690.00
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10mM * 1mL in DMSO
¥770.00
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生物活性
Discription JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor, with IC50 of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T.
产品信息
目录号 A15777
分子式 C19H21ClN6O3
分子量 416.86
CAS号 1700693-08-8
SMILES CNC1=NC(=NC2=C1C(=CN2)Cl)NC3=C(C=C(C=C3)C(=O)N4CCOCC4)OC
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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