JH-II-127
目录号: A15777
LRRK2 抑制剂
JH-II-127 是一种高效、选择性强且能穿透血脑屏障的 LRRK2 抑制剂,其 IC50 分别为 6.6 nM、2.2 nM、47.7 nM,针对 LRRK2-野生型、LRRK2-G2019S、LRRK2-A2016T。
Discription | JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor, with IC50 of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T. |
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目录号 | A15777 |
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分子式 | C19H21ClN6O3 |
分子量 | 416.86 |
CAS号 | 1700693-08-8 |
SMILES | CNC1=NC(=NC2=C1C(=CN2)Cl)NC3=C(C=C(C=C3)C(=O)N4CCOCC4)OC |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2