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JNJ 26854165

目录号: A10491
p53 activator
JNJ-26854165 是一种 p53激活剂,并且与AraC或多柔比星协同作用,以诱导 p53介导的凋亡,可能为急性白血病的治疗提供一种新的治疗方法。
Grouped product items
规格 价格 库存 数量
2mg
¥210.00
现货
5mg
¥315.00
现货
10mg
¥595.00
现货
25mg
¥1,330.00
现货
50mg
¥2,555.00
现货
100mg
¥3,850.00
现货
500mg
¥8,505.00
现货
10mM * 1mL in DMSO
¥455.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用JNJ 26854165发表的1篇文献
  • Chang SJ, .et al. , Arch Biochem Biophys, 2018, Jun 1;647:10-32 PMID: 29655550
  • 生物活性
    Discription JNJ-26854165 is one of p53-activating agents and synergizes with AraC or doxorubicin to induce p53-mediated apoptosis and may provide a novel therapeutic approach for the treatment of acute leukemias.
    产品信息
    目录号 A10491
    分子式 C21H20N4
    分子量 328.4
    CAS号 881202-45-5
    SMILES C1=CC=C2C(=C1)C(=CN2)CCNC3=CC=C(C=C3)NC4=CC=NC=C4
    其他名称 JNJ26854165
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 56 mg/mL (170.51 mM)
    Water Insoluble
    Ethanol 2 mg/mL (6.08 mM)
    In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 30.45 mL 152.25 mL 304.51 mL
    0.5 mM 6.09 mL 30.45 mL 60.9 mL
    1 mM 3.05 mL 15.23 mL 30.45 mL
    5 mM 0.61 mL 3.05 mL 6.09 mL
    Useful Calculator

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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