JNJ-37822681 dihydrochloride

Name: JNJ-37822681 dihydrochloride
SKU: A21470
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A21470

dopamine D2 receptor antagonist

JNJ-37822681 二盐酸盐是一种强效、特异性、中枢活性、快速解离的多巴胺D2受体拮抗剂，对多巴胺D2L受体具有中等结合亲和力（Ki = 158 nM），有望用于治疗精神分裂症和双相情感障碍。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥315.00	现货
25mg	¥700.00	现货
50mg	¥1,050.00	现货
100mg	¥1,645.00	现货
*10mM 1mL in DMSO**	¥210.00	现货
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SDS

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生物活性

Discription	JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder.

产品信息

目录号	A21470
分子式	C17H19Cl2F5N4
分子量	445.26
CAS号	2108806-02-4
SMILES	FC(C1=NN=C(NC2CCN(CC3=CC=C(F)C(F)=C3)CC2)C=C1)(F)F.Cl.Cl
其他名称	JNJ37822681, JNJ 37822681
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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