JNJ-38877605
目录号: A10493
c-Met 抑制剂
c-Met 抑制剂 JNJ-38877605 选择性地结合到 c-Met,从而抑制 c-Met 磷酸化并干扰 c-Met 信号传导途径。
Discription | c-Met inhibitor JNJ-38877605 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. | |||||
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Cell Research |
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目录号 | A10493 |
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分子式 | C19H13F2N7 |
分子量 | 377.4 |
CAS号 | 943540-75-8 |
SMILES | CN1C=C(C=N1)C2=NN3C(=NN=C3C(C4=CC5=C(C=C4)N=CC=C5)(F)F)C=C2 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 33 mg/mL (87.45 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.5 mL | 132.49 mL | 264.97 mL |
0.5 mM | 5.3 mL | 26.5 mL | 52.99 mL |
1 mM | 2.65 mL | 13.25 mL | 26.5 mL |
5 mM | 0.53 mL | 2.65 mL | 5.3 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2