JNJ-38877618

Name: JNJ-38877618
SKU: A18325
Price: 350 CNY
Rating: 5 (288 reviews)

目录号: A18325

c-Met 抑制剂

JNJ-38877618 是一种新型的、高效的、高度选择性的、口服生物利用度的 c-Met 酪氨酸激酶抑制剂，其对 WT、M1250T 和 Y1235D 突变体 MET 的 Kd 分别为 1.2、2.1 和 21 nM。

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Grouped product items
规格	价格	库存
1mg	¥350.00	现货
2mg	¥525.00	现货
5mg	¥910.00	现货
10mg	¥1,505.00	现货
25mg	¥3,080.00	现货
50mg	¥4,550.00	现货
100mg	¥6,510.00	现货
500mg	¥13,125.00	现货
*10mM 1mL in DMSO**	¥1,050.00	现货
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Data Sheet

SDS

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生物活性

Discription	JNJ-38877618 is a novel potent, highly selective, orally bioavailable c-Met tyrosine kinase inhibitor with Kd of 1.2, 2.1 and 21 nM for WT, M1250T and Y1235D mutants MET, respectively.

产品信息

目录号	A18325
分子式	C20H12F2N6
分子量	374.355
CAS号	943540-74-7
SMILES	FC(C1=CC=C2N=CC=CC2=C1)(F)C3=NN=C4C=CC(C5=CC=NC=C5)=NN43
其他名称	JNJ38877618, JNJ 38877618
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	9 mg/mL (24.04 mM)
	Water	Insoluble
	Ethanol	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.71 mL	133.56 mL	267.13 mL
0.5 mM	5.34 mL	26.71 mL	53.43 mL
1 mM	2.67 mL	13.36 mL	26.71 mL
5 mM	0.53 mL	2.67 mL	5.34 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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