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JNJ-42041935是有效的(pKi = 7.3-7.9)，2-氧戊二酸竞争性，可逆和选择性PHD酶抑制剂。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.85 mL | 144.24 mL | 288.48 mL |
| 0.5 mM | 5.77 mL | 28.85 mL | 57.7 mL |
| 1 mM | 2.88 mL | 14.42 mL | 28.85 mL |
| 5 mM | 0.58 mL | 2.88 mL | 5.77 mL |
*The above data is based on the productmolecular weight 346.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15793 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 346.65 |
| Formula | C12H6ClF3N4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1193383-09-3 |
| Synonyms | JNJ 42041935 |
| SMILES | C1=C2C(=CC(=C1Cl)OC(F)(F)F)N=C(N2)N3C=C(C=N3)C(=O)O |
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