TRC253, also known as JNJ63576253, is a potent and orally active androgen receptor antagonist.
Cell Research
Cell Line
Type
Value
Description
References
Cell Line
Type
Value
Description
References
VCaP
IC50
265 nM
Antiproliferative activity against human VCaP cells expressing wild-type androgen receptor assessed as reduction in cell viability incubated for 5 days in presence of R1881 by CellTiter-glo assay
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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