微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
JNJ-7706621是对CDK1/2具有最高效力的pan-CDK抑制剂，IC50为9 nM/4 nM，并且在无细胞分析中对CDK1/2的选择性是CDK3/4/6的6倍以上。它还能有效抑制极光A/B，对Plk1和Wee1没有活性。
| In vitro (25°C) | DMSO | 67 mg/mL (169.89 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 0.5% methylcellulose+0.2% Tween 80 | 13 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.35 mL | 126.77 mL | 253.55 mL |
| 0.5 mM | 5.07 mL | 25.35 mL | 50.71 mL |
| 1 mM | 2.54 mL | 12.68 mL | 25.35 mL |
| 5 mM | 0.51 mL | 2.54 mL | 5.07 mL |
*The above data is based on the productmolecular weight 394.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10494 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 394.4 |
| Formula | C15H12F2N6O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 443797-96-4 |
| Synonyms | JNJ7706621 |
| SMILES | C1=CC(=C(C(=C1)F)C(=O)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Flavopiridol (Alvocidib)
Flavopiridol（Alvocidib）是一种细胞周期蛋白依赖性激酶抑制剂，与ATP竞争性抑制CDK，包括CDK1， CDK2， CDK4和CDK…
AT7519 trifluoroacetate
AT7519 trifluoroacetate是CDK1、2、4、6和9的多CDK抑制剂，IC50为10-210 nM，对CDK3的效力较低，对CDK7的活性较低。
Flavopiridol HCl
Flavopiridol HCl是细胞周期蛋白依赖性激酶的抑制剂。（-）-顺式形式诱导特定肿瘤细胞的凋亡。
LEE011 (Ribociclib)
LEE011 (Ribociclib)是一种可口服的细胞周期蛋白依赖性激酶（CDK）抑制剂，靶向细胞周期蛋白D1/CDK4和细胞周期…
Kenpaullone
Kenpaullone是CDK1/细胞周期蛋白B（IC 50 = 400 nM），CDK2/细胞周期蛋白A（IC 50 = 680nM），CDK5（IC 50 = 850nM）的有效…
Keywords:购买 JNJ-7706621 | JNJ-7706621 供应商 | 订购 JNJ-7706621 | JNJ-7706621 价格 | JNJ-7706621 生产商 | 订单 JNJ-7706621 | JNJ-7706621 代理商 | 购买 443797-96-4| 443797-96-4 供应商 | 订购 443797-96-4 | 443797-96-4 价格 | 443797-96-4 生产商 | 订单 443797-96-4 | 443797-96-4 代理商|buy JNJ-7706621 | JNJ-7706621 Supplier | purchase JNJ-7706621 | JNJ-7706621 cost | JNJ-7706621 manufacturer | order JNJ-7706621 | JNJ-7706621 distributor | buy 443797-96-4| 443797-96-4 Supplier | purchase 443797-96-4 | 443797-96-4 cost | 443797-96-4 manufacturer | order 443797-96-4 | 443797-96-4 distributor