(+)-JQ1

Name: (+)-JQ1
SKU: A12729
Price: 175 CNY
Rating: 5 (12 reviews)

目录号: A12729

BET 抑制剂

12 篇发表文献

(+)-JQ1 是一种高效、高亲和力、选择性的 BET 溴结构域抑制剂。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥210.00	现货
5mg	¥315.00	现货
10mg	¥455.00	现货
25mg	¥630.00	现货
50mg	¥980.00	现货
100mg	¥1,330.00	现货
200mg	¥2,030.00	现货
500mg	¥3,710.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of (+)-JQ1

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用(+)-JQ1发表的12篇文献

Kei Taga, .et al. , Microbiol Immunol, 2024, Mar;68(3):90-99 PMID: 38244193

Deeksha Sharma, .et al. , Breast Cancer Res, 2023, Nov 15;25(1):144 PMID: 37968653

Adriana K Alexander, .et al. , Nat Commun, 2023, Mar 29;14(1):1753 PMID: 36990976

Haruki Kitamura, .et al. , Biochem Biophys Res Commun, 2023, Jan 22;641:139-147 PMID: 36527748

Gerald Thiel, .et al. , Pharmaceuticals (Basel), 2022, Jul 10;15(7):846 PMID: 35890145

Selase D Deletsu, .et al. , Biochem Biophys Res Commun, 2021, Aug 27;567:106-111 PMID: 34146904

Cole Schonhofer, .et al. , Biochem Pharmacol, 2021, Apr;186:114462 PMID: 33577894

Nandini Verma, .et al. , Sci Adv, 2020, 6 : eaba8968

Kuo MT, .et al. , Transl Oncol, 2020, 13(2):355-364 PMID: 31887630

Rao Z, .et al. , J Immunol, 2019, Aug 15;203(4):1031-1043 PMID: 31300512

A Carrer, .et al. , Cancer Discov, 2019, Jan 9. pii: CD-18-0567 PMID: 30626590

Clocchiatti A, .et al. , J Clin Invest, 2018, Dec 3;128(12):5531-5548 PMID: 30395538

生物活性

Discription

(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12729
分子式	C23H25ClN4O2S
分子量	456.99
CAS号	1268524-70-4
SMILES	CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 90 mg/mL (196.93 mM)
	Water	Insoluble
	Ethanol	90 mg/mL
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.88 mL	109.41 mL	218.82 mL
0.5 mM	4.38 mL	21.88 mL	43.76 mL
1 mM	2.19 mL	10.94 mL	21.88 mL
5 mM	0.44 mL	2.19 mL	4.38 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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