JTE-952

Name: JTE-952
SKU: A18391
Price: 2415 CNY
Rating: 5 (288 reviews)

目录号: A18391

CSF-1R 抑制剂

TE-952 是一种强效的、口服活性的、选择性 Type II 抑制剂，针对 集落刺激因子-1 受体（CSF-1R 或 cFMS，III型受体酪氨酸激酶），其 IC50 值分别针对 CSF1R 和 TrkA 为 13 nM 和 261 nM。对小鼠胶原诱导的关节炎模型有效。

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规格	价格	库存
5mg	¥2,415.00	现货
10mg	¥4,515.00	现货
25mg	¥9,520.00	现货
50mg	¥13,965.00	现货
100mg	¥21,665.00	现货
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Data Sheet

SDS

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生物活性

Discription

TE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A18391
分子式	C30H34N2O6
分子量	518.6
CAS号	1255303-54-8
SMILES	O=C(N1CC(C2=CC=C(OCC3=CC=C(C4CC4)C=C3)C(OC)=C2)C1)C5=NC=CC(COC[C@@H](O)CO)=C5
其他名称	JTE952. JTE 952
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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