JZL195
JZL195 是一种选择性且有效的双重 FAAH/MAGL 抑制剂,其 IC50 分别为 13 nM 和 19 nM,针对小鼠大脑的 FAAH 和 MAGL。
Discription | JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor with IC50 of 13 nM and 19 nM for mouse brain FAAH and MAGL respectively. |
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目录号 | A12390 |
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分子式 | C24H23N3O5 |
分子量 | 433.46 |
CAS号 | 1210004-12-8 |
SMILES | O=C(N1CCN(CC2=CC=CC(OC3=CC=CC=C3)=C2)CC1)OC(C=C4)=CC=C4[N+]([O-])=O |
其他名称 | JZL 195, JZL-195 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 42 mg/mL (96.89 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.07 mL | 115.35 mL | 230.7 mL |
0.5 mM | 4.61 mL | 23.07 mL | 46.14 mL |
1 mM | 2.31 mL | 11.54 mL | 23.07 mL |
5 mM | 0.46 mL | 2.31 mL | 4.61 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2