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K145是一种选择性SphK2抑制剂，IC50为4.30±0.06μM，而在浓度不超过10 uM时，对SphK1无抑制作用。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.7 mL | 143.49 mL | 286.98 mL |
| 0.5 mM | 5.74 mL | 28.7 mL | 57.4 mL |
| 1 mM | 2.87 mL | 14.35 mL | 28.7 mL |
| 5 mM | 0.57 mL | 2.87 mL | 5.74 mL |
*The above data is based on the productmolecular weight 348.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16288 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 348.46 |
| Formula | C18H24N2O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1309444-75-4 |
| Synonyms | SphK2 inhibitor, K 145, K-145 |
| SMILES | CCCCOC1=CC=C(C=C1)CCC=C2C(=O)N(C(=O)S2)CCN |
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