Asmaa R. Abdel-Hamed, .et al. , J Med Chem Sci, 2023, 6: 250-268
A O Hamouda, .et al. , Eur Rev Med Pharmacol Sci, 2022, Dec;26(23):8644-8659 PMID: 36524484
生物活性
Discription
Kaempferol is found to inhibit bovine aorta myosin light chain kinase with a Ki of 0.3-0.5 microM and also is found to inhibit VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway.
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
产品信息
目录号
A10495
分子式
C15H10O6
分子量
286.2
CAS号
520-18-3
SMILES
C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
储存条件
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
溶解性数据
In vitro
DMSO
Warmed: 53 mg/mL (185.17 mM)
Water
Insoluble
Ethanol
3 mg/mL (10.48 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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