KDM2A/7A-IN-1

目录号: A19724
KDM2A/7A inhibitor
KDM2A/7A-IN-1 是首创的、选择性的、细胞渗透性的组蛋白赖氨酸去甲基化酶 KDM2A/7A 抑制剂,对 KDM2A 的 IC50 为 0.16 μM,对其他 JmjC 赖氨酸去甲基化酶具有 75 倍的选择性,并且对甲基转移酶和组蛋白乙酰转移酶无活性。
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规格 价格 库存 数量
1mg
¥1,855.00
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5mg
¥4,585.00
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10mg
¥7,385.00
现货
25mg
¥14,595.00
现货
50mg
¥19,425.00
现货
100mg
¥25,865.00
现货
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生物活性
Discription KDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of histone lysine demethylases KDM2A/7A, with an IC50 of 0.16?μM for KDM2A, exhibits 75 fold selevtivity over other JmjC lysine demethylases, and is inactive on methyl transferases, and histone acetyl transferases.
产品信息
目录号 A19724
分子式 C33H38N4O
分子量 506.68
CAS号 2169272-46-0
SMILES CC(N([C@@H](C1=CN=CC(CCCCCCCN2CCCC2)=C1)[C@@]3(C4=CC=CC=C4)C#N)C5=C3C=CC=C5)=O
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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