KDM5A-IN-1

目录号: A20436
KDM5 inhibitor
KDM5A-IN-1 是一种效力强大的、口服生物利用度高的全组蛋白赖氨酸去甲基化酶5(KDM5)抑制剂,其对 KDM5A、KDM5B 和 KDM5C 的 IC50 分别为 45 nM、56 nM 和 55 nM,对 PC9 H3K4Me3 的 EC50 值为 960 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥945.00
现货
5mg
¥2,205.00
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10mg
¥3,185.00
现货
50mg
¥9,625.00
现货
100mg
¥15,400.00
现货
10mM * 1mL in DMSO
¥2,730.00
现货
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生物活性
Discription KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A20436
分子式 C15H22N4O2
分子量 290.36
CAS号 1905481-36-8
SMILES O=C(C1CC1)N[C@@H]2CCN(C(C3=CC(C(C)C)=NN3)=O)C2
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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