KDM5A-IN-1
目录号: A20436
KDM5 inhibitor
KDM5A-IN-1 是一种效力强大的、口服生物利用度高的全组蛋白赖氨酸去甲基化酶5(KDM5)抑制剂,其对 KDM5A、KDM5B 和 KDM5C 的 IC50 分别为 45 nM、56 nM 和 55 nM,对 PC9 H3K4Me3 的 EC50 值为 960 nM。
Discription | KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. | |||||
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Cell Research |
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目录号 | A20436 |
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分子式 | C15H22N4O2 |
分子量 | 290.36 |
CAS号 | 1905481-36-8 |
SMILES | O=C(C1CC1)N[C@@H]2CCN(C(C3=CC(C(C)C)=NN3)=O)C2 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2