微信关注
China
Total item
Cart Subtotal
￥ 0.00 产品详情
Kenpaullone是CDK1/细胞周期蛋白B（IC 50 = 400 nM），CDK2/细胞周期蛋白A（IC 50 = 680nM），CDK5（IC 50 = 850nM）的有效抑制剂，对其他激酶的作用要小得多。
Targets
| Target | Value |
|---|---|
| GSK-3β | IC50: 0.23μM |
| CDK1/CyclinB | IC50: 0.4μM |
| CDK2/CyclinA | IC50: 0.68μM |
| CDK5/p35 | IC50: 0.85μM |
| CDK2/CyclinE | IC50: 7.5μM |
| ERK2 | IC50: 9μM |
| c-Src | IC50: 15μM |
| CaseinKinase2 | IC50: 20μM |
| ERK1 | IC50: 20μM |
| In vitro (25°C) | DMSO | 58 mg/mL (177.27 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+50% PEG 300+5% Tween 80+ddH2O | 2.3 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.56 mL | 152.81 mL | 305.62 mL |
| 0.5 mM | 6.11 mL | 30.56 mL | 61.12 mL |
| 1 mM | 3.06 mL | 15.28 mL | 30.56 mL |
| 5 mM | 0.61 mL | 3.06 mL | 6.11 mL |
*The above data is based on the productmolecular weight 327.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11220 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 327.2 |
| Formula | C16H11BrN2O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 142273-20-9 |
| SMILES | C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)Br |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
PHA-793887
PHA-793887是一种新型有效的CDK2，CDK5和CDK7抑制剂，IC50分别为8 nM，5 nM 和10 nM，作用于CDK2，5，和7比作用于CDK1…
LY2835219 (abemaciclib)
LY2835219 (abemaciclib)是一种细胞周期蛋白依赖性激酶（CDK）抑制剂，靶向CDK4（cyclin D1）和CDK6（cyclin D3）细胞…
BMS-265246
BMS-265246是cdk2/cyclin E和cdk1/cyclin B以及cdk4/cyclin D的强新吡唑并吡啶抑制剂。
Keywords:购买 Kenpaullone | Kenpaullone 供应商 | 订购 Kenpaullone | Kenpaullone 价格 | Kenpaullone 生产商 | 订单 Kenpaullone | Kenpaullone 代理商 | 购买 142273-20-9| 142273-20-9 供应商 | 订购 142273-20-9 | 142273-20-9 价格 | 142273-20-9 生产商 | 订单 142273-20-9 | 142273-20-9 代理商|buy Kenpaullone | Kenpaullone Supplier | purchase Kenpaullone | Kenpaullone cost | Kenpaullone manufacturer | order Kenpaullone | Kenpaullone distributor | buy 142273-20-9| 142273-20-9 Supplier | purchase 142273-20-9 | 142273-20-9 cost | 142273-20-9 manufacturer | order 142273-20-9 | 142273-20-9 distributor
联系我们
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
Not your Region? View all Distributors
最近查看过的产品
ADOOQ 产品质量保证
We promise all products to perform as described.