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KIN001-051是一种有效的、选择性的Lck抑制剂。淋巴细胞特异性蛋白酪氨酸激酶（Lck）是非受体蛋白酪氨酸激酶Src家族的成员，在触发细胞因子产生的T细胞受体信号转导的初始步骤中起着至关重要的作用。
| In vitro | DMSO | 18 mg/mL (48.58 mM) | |
| Water | Insoluble | ||
| Ethanol | 4 mg/mL (10.79 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.99 mL | 134.97 mL | 269.93 mL |
| 0.5 mM | 5.4 mL | 26.99 mL | 53.99 mL |
| 1 mM | 2.7 mL | 13.5 mL | 26.99 mL |
| 5 mM | 0.54 mL | 2.7 mL | 5.4 mL |
*The above data is based on the productmolecular weight 370.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16923 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 370.46 |
| Formula | C23H22N4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 213743-31-8 |
| Synonyms | KIN001051, KIN001 051 |
| SMILES | NC1=C2C(N(C3CCCC3)C=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1 |
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