KIRA6
目录号: A12516
IRE1α RNase kinase inhibitor
KIRA6 是一种先进的小分子 IRE1α RNase 激酶抑制剂，其 IC50 为 0.6 μM。KIRA6 能够触发凋亡反应。
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生物活性
| Discription | KIRA6 is an advanced small-molecule IRE1α RNase kinase inhibitor with an IC50 of 0.6 ?M. KIRA6 can trigger an apoptotic response. |
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产品信息
| 目录号 | A12516 |
|---|---|
| 分子式 | C28H25F3N6O |
| 分子量 | 518.53 |
| CAS号 | 1589527-65-0 |
| SMILES | O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=C3C=CC=CC3=C(C4=C5C(N)=NC=CN5C(C(C)(C)C)=N4)C=C2 |
| 其他名称 | KIRA-6 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 59 mg/mL (113.78 mM) | |
| Water | Insoluble | ||
| Ethanol | 59 mg/mL (113.78 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.29 mL | 96.43 mL | 192.85 mL |
| 0.5 mM | 3.86 mL | 19.29 mL | 38.57 mL |
| 1 mM | 1.93 mL | 9.64 mL | 19.29 mL |
| 5 mM | 0.39 mL | 1.93 mL | 3.86 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1589527-65-0 | 1589527-65-0 供应商 | 1589527-65-0 花费 | 1589527-65-0 生产商 | 订购 1589527-65-0 | 1589527-65-0 代理商