主页 /
Kira8 (AMG-18)

Kira8 (AMG-18)

Name: Kira8 (AMG-18)
SKU: A18641

目录号: A18641

mono-selective IRE1α inhibitor

Kira8 (AMG-18) Chemical Structure

CAS NO. 1630086-20-2

Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.

库存：缺货

规格	价格
5 mg	￥ 1,400.00
10 mg	￥ 2,240.00
50 mg	￥ 7,000.00
100 mg	￥ 10,360.00

注册以在此产品重新有库存时获得通知

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.64 mL	83.18 mL	166.36 mL
0.5 mM	3.33 mL	16.64 mL	33.27 mL
1 mM	1.66 mL	8.32 mL	16.64 mL
5 mM	0.33 mL	1.66 mL	3.33 mL

*The above data is based on the productmolecular weight 601.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18641
作用机制	Inhibitor (抑制剂)
M. Wt	601.12
Formula	C31H29ClN6O3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1630086-20-2
Synonyms	AMG 18, AMG18
SMILES	O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(OC4=NC=CC=C4C5=NC(N[C@@H]6CNCCC6)=NC=C5)C3=CC=C2)=O