Kira8 (AMG-18)
目录号: A18641
mono-selective IRE1α inhibitor
Kira8 (AMG-18) 是一种单一选择性的 IRE1α 抑制剂,它通过变构方式减弱 IRE1α RNase 活性,其 IC50 为 5.9 nM。
Discription | Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM. | |||||
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Cell Research |
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目录号 | A18641 |
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分子式 | C31H29ClN6O3S |
分子量 | 601.12 |
CAS号 | 1630086-20-2 |
SMILES | O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(OC4=NC=CC=C4C5=NC(N[C@@H]6CNCCC6)=NC=C5)C3=CC=C2)=O |
其他名称 | AMG 18, AMG18 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2