Kira8 Hydrochloride
目录号: A21780
IRE1α inhibitor
Kira8 Hydrochloride (AMG-18 Hydrochloride) 是一种单选择性 IRE1α 抑制剂,它通过变构方式减弱 IRE1α RNase 活性,其 IC50 为 5.9 nM。
Discription | Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM. |
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目录号 | A21780 |
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分子式 | C31H30Cl2N6O3S |
分子量 | 637.58 |
CAS号 | 2250019-92-0 |
SMILES | O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(C3=CC=C2)OC4=NC=CC=C4C5=NC(N[C@H]6CNCCC6)=NC=C5)=O.[H]Cl |
其他名称 | AMG-18 Hydrochloride, AMG18, AMG 18; Kira-8, Kira 8 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2