微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
KM 11060纠正了F508del-CFTR的运输，增加了质膜上功能性CFTR的量（?75％）并抑制了PDE5的活性。
| In vitro | DMSO | 81 mg/mL (191.79 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (4.73 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.68 mL | 118.39 mL | 236.78 mL |
| 0.5 mM | 4.74 mL | 23.68 mL | 47.36 mL |
| 1 mM | 2.37 mL | 11.84 mL | 23.68 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.74 mL |
*The above data is based on the productmolecular weight 422.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15843 |
|---|---|
| M. Wt | 422.33 |
| Formula | C19H17Cl2N3O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 774549-97-2 |
| Synonyms | KM-11060, KM11060 |
| SMILES | O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C(Cl)C=C4)=O |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
ML 786 dihydrochloride
ML 786 dihydrochloride是一种有效的Raf激酶抑制剂（B-RafV600E，C-Raf和野生型B-Raf的IC50值分别为2.1、2.5和4.2 nM）。
PLX4032 (Vemurafenib)
PLX4032(Vemurafenib)也称为RG7204，Vemurafenib，R7204，RO5185426。PLX4032是B-raf抑制剂，IC50为44 nM。
Raf265 derivative
Raf265 derivative是Raf265的衍生物，Raf265是一种口服，高度选择性的RAF和VEGFR激酶抑制剂，IC50为5至10μM。
Dabrafenib Mesylate
Dabrafenib Mesylate是一种新颖，有效和选择性的Raf激酶抑制剂，能够抑制野生型B-Raf，B-RafV600E和c-Raf的激酶活…
Balamapimod (MKI-833)
Balamapimod (MKI-833)是Ras/Raf/MEK抑制剂。
Keywords:购买 KM 11060 | KM 11060 供应商 | 订购 KM 11060 | KM 11060 价格 | KM 11060 生产商 | 订单 KM 11060 | KM 11060 代理商 | 购买 774549-97-2 | 774549-97-2 供应商 | 订购 774549-97-2 | 774549-97-2 价格 | 774549-97-2 生产商 | 订单 774549-97-2 | 774549-97-2 代理商|buy KM 11060 | KM 11060 Supplier | purchase KM 11060 | KM 11060 cost | KM 11060 manufacturer | order KM 11060 | KM 11060 distributor | buy 774549-97-2 | 774549-97-2 Supplier | purchase 774549-97-2 | 774549-97-2 cost | 774549-97-2 manufacturer | order 774549-97-2 | 774549-97-2 distributor