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KN-92 phosphate是KN-93的非活性衍生物。KN-93是Ca2+/钙调蛋白依赖性激酶II（CaMKII）的选择性抑制剂，竞争性阻断CaM与激酶的结合（Ki = 370 nM）。
| In vitro | DMSO | 85 mg/mL (153.15 mM) | |
| Water | Insoluble | ||
| Ethanol | 9 mg/mL (16.21 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.02 mL | 90.09 mL | 180.19 mL |
| 0.5 mM | 3.6 mL | 18.02 mL | 36.04 mL |
| 1 mM | 1.8 mL | 9.01 mL | 18.02 mL |
| 5 mM | 0.36 mL | 1.8 mL | 3.6 mL |
*The above data is based on the productmolecular weight 554.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15139 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 554.98 |
| Formula | C24H28ClN2O7PS |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1135280-28-2 |
| Synonyms | KN 92 phosphate, KN92 phosphate |
| SMILES | CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2NS(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O |
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