KN-92 phosphate
目录号: A15139
CaMKII 抑制剂
KN-92 是 KN-93 的非活性衍生物。KN-93 是一种选择性的 Ca2+/钙调蛋白依赖性激酶II(CaMKII) 抑制剂,它通过竞争性阻断钙调蛋白与激酶的结合来发挥作用(Ki = 370 nM)。
Discription | KN-92 is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
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目录号 | A15139 |
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分子式 | C24H28ClN2O7PS |
分子量 | 554.98 |
CAS号 | 1135280-28-2 |
SMILES | CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2NS(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O |
其他名称 | KN 92 phosphate, KN92 phosphate |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 85 mg/mL (153.15 mM) | |
Water | Insoluble | ||
Ethanol | 9 mg/mL (16.21 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.02 mL | 90.09 mL | 180.19 mL |
0.5 mM | 3.6 mL | 18.02 mL | 36.04 mL |
1 mM | 1.8 mL | 9.01 mL | 18.02 mL |
5 mM | 0.36 mL | 1.8 mL | 3.6 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2