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KN-92是KN-93的非活性衍生物。KN-93是Ca2+/钙调蛋白依赖性激酶II(CaMKII)的选择性抑制剂,竞争性阻断CaM与激酶的结合(Ki = 370 nM)。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.88 mL | 109.41 mL | 218.83 mL |
0.5 mM | 4.38 mL | 21.88 mL | 43.77 mL |
1 mM | 2.19 mL | 10.94 mL | 21.88 mL |
5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
*The above data is based on the productmolecular weight 456.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A15137 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 456.98 |
Formula | C24H25ClN2O3S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 176708-42-2 |
Synonyms | KN 92, KN92 |
SMILES | CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2NS(=O)(=O)C3=CC=C(C=C3)OC |
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