KO-947

Name: KO-947
SKU: A19903
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A19903

ERK1/2 kinases inhibitor

KO-947 是一种强效且选择性的 ERK1/2 激酶 抑制剂，具有潜在的临床应用价值，用于治疗 MAPK 通路 紊乱的肿瘤。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥700.00	现货
10mg	¥1,120.00	现货
25mg	¥2,345.00	现货
50mg	¥3,780.00	现货
100mg	¥5,880.00	现货
更大包装	更多折扣

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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

KO-947 is a potent and selective inhibitor of ERK1/2 kinases with potential clinical utility in MAPK pathway dysregulated tumors.

Targets

Target	Value

产品信息

目录号	A19903
分子式	C21H17N5O
分子量	355.39
CAS号	1695533-89-1
SMILES	O=C1NC2=CC(NN=C3C4=CC=NC=C4)=C3C=C2CN1CC5=CC=CC=C5
其他名称	KO947, KO 947
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	62 mg/mL (174.46 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.14 mL	140.69 mL	281.38 mL
0.5 mM	5.63 mL	28.14 mL	56.28 mL
1 mM	2.81 mL	14.07 mL	28.14 mL
5 mM	0.56 mL	2.81 mL	5.63 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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