Kobe2602
目录号: A12578
Ras?€?Raf 抑制剂
Kobe2602 是 Kobe0065 的类似物。展示出强大的活性,以竞争性抑制 H-Ras??GTP 与 c-Raf-1 RBD 的结合,Ki 值为 149 ± 55 μM。
Discription | Kobe2602 is an analog of Kobe0065. Exhibits potent activity to competitively inhibit the binding of H-Ras??GTP to c-Raf-1 RBD with a Ki value of 149 ?? 55 μM. |
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目录号 | A12578 |
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分子式 | C14H9F4N5O4S |
分子量 | 419.31 |
CAS号 | 454453-49-7 |
SMILES | C1=CC(=CC=C1NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])F |
其他名称 | Kobe-2602 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 79 mg/mL (188.4 mM) | |
Water | Insoluble | ||
Ethanol | 38 mg/mL (90.62 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.85 mL | 119.24 mL | 238.49 mL |
0.5 mM | 4.77 mL | 23.85 mL | 47.7 mL |
1 mM | 2.38 mL | 11.92 mL | 23.85 mL |
5 mM | 0.48 mL | 2.38 mL | 4.77 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2