KRCA-0008
目录号: A15511
ACK1/ALK inhibitor
KRCA-0008 是一种强效且选择性的 ALK/Ack1 抑制剂,其 IC50 分别为 ALK 的 12 nM 和 Ack1 的 4 nM;显示出药物样特性,且没有 hERG 责任。
Discription | KRCA-0008 is a potent and selective ALK/Ack1 inhibitor with IC50 of 12 nM/4 nM for ALK and Ack1 respectively; displays drug-like properties without hERG liability. |
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目录号 | A15511 |
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分子式 | C30H37ClN8O4 |
分子量 | 609.12 |
CAS号 | 1472795-20-2 |
SMILES | CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC(=NC=C3Cl)NC4=C(C=C(C=C4)N5CCN(CC5)C(=O)C)OC)OC |
其他名称 | KRCA 0008, KRCA0008 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2