产品详情
KRCA-0008是一种有效的选择性ALK/Ack1抑制剂,对ALK和Ack1的IC50分别为12 nM/4 nM。表现出类似药物的性质而无hERG责任。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.42 mL | 82.09 mL | 164.17 mL |
0.5 mM | 3.28 mL | 16.42 mL | 32.83 mL |
1 mM | 1.64 mL | 8.21 mL | 16.42 mL |
5 mM | 0.33 mL | 1.64 mL | 3.28 mL |
*The above data is based on the productmolecular weight 609.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A15511 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 609.12 |
Formula | C30H37ClN8O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1472795-20-2 |
Synonyms | KRCA 0008, KRCA0008 |
SMILES | CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC(=NC=C3Cl)NC4=C(C=C(C=C4)N5CCN(CC5)C(=O)C)OC)OC |
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