KU-55933

Name: KU-55933
SKU: A10506
Price: 245 CNY
Rating: 5 (6 reviews)

目录号: A10506

ATM 抑制剂

6 篇发表文献

KU-55933 是一种 ATM 抑制剂，通过抑制细胞增殖并通过阻断在癌细胞中过度激活的 Akt 来诱导凋亡。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥385.00	现货
25mg	¥665.00	现货
50mg	¥1,120.00	现货
100mg	¥1,960.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用KU-55933发表的6篇文献

Ryo Sakasai, .et al. , Biochem Biophys Res Commun, 2023, Aug 6;668:42-48 PMID: 37244033

Atsushi Saito, .et al. , Cell Rep, 2023, May 30;42(5):112479 PMID: 37178686

Mariko Shikata, .et al. , Chem Res Toxicol, 2021, Dec 20;34(12):2512-2521 PMID: 34784199

Masaya Igase, .et al. , Mol Ther Oncolytics, 2019, vol 15 PMID: 31650025

Hayakawa K, .et al. , Biochem Biophys Res Commun, 2018, Dec 2;506(4):983-989 PMID: 30404732

Chwastek J, .et al. , Int J Biochem Cell Biol, 2017, Jun;87:38-53 PMID: 28341201

生物活性

Discription

KU-55933 is an ATM inhibitor by suppressing cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10506
分子式	C21H17NO3S2
分子量	395.5
CAS号	587871-26-9
SMILES	C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	29 mg/mL (73.33 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+40%PEG300+5%Tween80+50%ddH2O	3.75 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.28 mL	126.42 mL	252.84 mL
0.5 mM	5.06 mL	25.28 mL	50.57 mL
1 mM	2.53 mL	12.64 mL	25.28 mL
5 mM	0.51 mL	2.53 mL	5.06 mL

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