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Tirbanibulin dihydrochloride是首个靶向Src肽底物位点的临床Src抑制剂(拟肽类),在癌细胞系中GI50为9-60 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.82 mL | 99.12 mL | 198.24 mL |
| 0.5 mM | 3.96 mL | 19.82 mL | 39.65 mL |
| 1 mM | 1.98 mL | 9.91 mL | 19.82 mL |
| 5 mM | 0.4 mL | 1.98 mL | 3.96 mL |
*The above data is based on the productmolecular weight 504.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11471 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 504.45 |
| Formula | C26H31Cl2N3O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1038395-65-1 |
| Synonyms | KX2-391 2HCl, KX2-391 |
| SMILES | C1COCCN1CCOC2=CC=C(C=C2)C3=CN=C(C=C3)CC(=O)NCC4=CC=CC=C4.Cl.Cl |
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