KY1220

目录号: A20284

Wnt/beta-catenin modulator

KY1220 是一种化合物,通过靶向 Wnt/β-catenin 通路,能够破坏 β-cateninRas,在 HEK293 报告细胞中的 IC50 为 2.1 μM。
Grouped product items
规格 价格 库存 数量
2mg
¥210.00
现货
5mg
¥455.00
现货
10mg
¥770.00
现货
25mg
¥1,855.00
现货
50mg
¥2,695.00
现货
100mg
¥3,955.00
现货
200mg
¥5,390.00
现货
10mM * 1mL in DMSO
¥420.00
现货
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生物活性
Discription KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway; with an IC50 of 2.1 μM in HEK293 reporter cells.
产品信息
目录号 A20284
分子式 C14H10N4O3S
分子量 314.32
CAS号 292168-79-7
SMILES O=C(/C(N1)=C/C2=CC=CN2C3=CC=C([N+]([O-])=O)C=C3)NC1=S
其他名称 KY 1220, KY-1220
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 59 mg/mL (187.7 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.81 mL 159.07 mL 318.15 mL
0.5 mM 6.36 mL 31.81 mL 63.63 mL
1 mM 3.18 mL 15.91 mL 31.81 mL
5 mM 0.64 mL 3.18 mL 6.36 mL
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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
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