KY1220
目录号: A20284
Wnt/beta-catenin modulator
KY1220 是一种化合物,通过靶向 Wnt/β-catenin 通路,能够破坏 β-catenin 和 Ras,在 HEK293 报告细胞中的 IC50 为 2.1 μM。
Wnt/beta-catenin modulator
Discription | KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway; with an IC50 of 2.1 μM in HEK293 reporter cells. |
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目录号 | A20284 |
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分子式 | C14H10N4O3S |
分子量 | 314.32 |
CAS号 | 292168-79-7 |
SMILES | O=C(/C(N1)=C/C2=CC=CN2C3=CC=C([N+]([O-])=O)C=C3)NC1=S |
其他名称 | KY 1220, KY-1220 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 59 mg/mL (187.7 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 31.81 mL | 159.07 mL | 318.15 mL |
0.5 mM | 6.36 mL | 31.81 mL | 63.63 mL |
1 mM | 3.18 mL | 15.91 mL | 31.81 mL |
5 mM | 0.64 mL | 3.18 mL | 6.36 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2