KZR-504
目录号: A19210
LMP2 抑制剂
KZR-504 是一种高度选择性的免疫蛋白酶体低分子量多肽2(LMP2)抑制剂,其半抑制浓度(IC50)分别为51纳摩尔(nM)和4.274微摩尔(μM)针对 LMP2 和 LMP7。KZR-504 对于治疗自身免疫疾病具有研究兴趣。
Discription | KZR-504 is a highly selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2), with IC50s of 51 nM, 4.274 μM for LMP2 and LMP7, respectively. KZR-504 is of interest for the treatment of autoimmune disease. | |||||
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Cell Research |
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目录号 | A19210 |
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分子式 | C21H23N3O6 |
分子量 | 413.42 |
CAS号 | 1629052-78-3 |
SMILES | O=C(N[C@@H](CO)C(N[C@@H](CC1=CC=CC=C1)C([C@]2(CO2)C)=O)=O)C(N3)=CC=CC3=O |
其他名称 | KZR 504; KZR504 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2