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Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity?=?255:1, a half-life of 4?min)?? acts as an adrenoceptor antagonist.
| In vitro | DMSO | 89 mg/mL (162.99 mM) | |
| Water | 89 mg/mL (162.99 mM) | ||
| Ethanol | 37 mg/mL (67.75 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.31 mL | 91.57 mL | 183.13 mL |
| 0.5 mM | 3.66 mL | 18.31 mL | 36.63 mL |
| 1 mM | 1.83 mL | 9.16 mL | 18.31 mL |
| 5 mM | 0.37 mL | 1.83 mL | 3.66 mL |
*The above data is based on the productmolecular weight 546.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17675 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 546.05 |
| Formula | C25H40ClN3O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 144481-98-1 |
| Synonyms | ONO1101 hydrochloride, ONO 1101, ONO-1101 |
| SMILES | O=C(OC[C@H]1OC(C)(C)OC1)CCC2=CC=C(OC[C@@H](O)CNCCNC(N3CCOCC3)=O)C=C2.[H]Cl |
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