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Lck inhibitor 2 是酪氨酸激酶的双苯胺基嘧啶抑制剂，包括LCK，BTK，LYN，SYK和TXK。Lck，Btk，Lyn，Btk和Txk的IC50值分别为13nM，9nM，3nM，26nM和2nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.82 mL | 149.09 mL | 298.19 mL |
| 0.5 mM | 5.96 mL | 29.82 mL | 59.64 mL |
| 1 mM | 2.98 mL | 14.91 mL | 29.82 mL |
| 5 mM | 0.6 mL | 2.98 mL | 5.96 mL |
*The above data is based on the productmolecular weight 335.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15141 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 335.36 |
| Formula | C18H17N5O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 944795-06-6 |
| SMILES | CC1=C(C=C(C=C1)O)NC2=NC(=NC=C2)NC3=CC=CC(=C3)C(=O)N |
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