Lck inhibitor 2
目录号: A15141
Lck 抑制剂
Lck inhibitor 2 是一种双苯胺嘧啶抑制剂,能够抑制包括 LCK、BTK、LYN、SYK 和 TXK 在内的酪氨酸激酶。其半抑制浓度(IC50)分别为 LCK 13nM、BTK 9nM、LYN 3nM、SYK 26nM 和 TXK 2nM。
Discription | Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK. The IC50 values are 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk, Lyn, Btk and Txk respectively . |
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目录号 | A15141 |
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分子式 | C18H17N5O2 |
分子量 | 335.36 |
CAS号 | 944795-06-6 |
SMILES | CC1=C(C=C(C=C1)O)NC2=NC(=NC=C2)NC3=CC=CC(=C3)C(=O)N |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2