LDC1267
目录号: A13003
TAM Receptor 抑制剂
LDC1267 是一种高度选择性的 TAM（Tyro3、Axl 和 Mer）激酶抑制剂，其 IC50 分别针对 Tyro3、Axl 和 Mer 为小于 5 nM、8 nM 和 29 nM。
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生物活性
| Discription | LDC1267 is a highly selective TAM(Tyro3, Axl and Mer) kinase inhibitor with IC50 of <5 nM/8 nM/29 nM for Tyro3,Axl and Mer respectively. | |||||
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| Cell Research |
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产品信息
| 目录号 | A13003 |
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| 分子式 | C30H26F2N4O5 |
| 分子量 | 560.55 |
| CAS号 | 1361030-48-9 |
| SMILES | CCOC1=CN(N=C1C(=O)NC2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)F)C5=C(C=C(C=C5)F)C |
| 其他名称 | LDC 1267, LDC-1267 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Warmed: 89 mg/mL (158.77 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 2 mg/mL (3.56 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.84 mL | 89.2 mL | 178.4 mL |
| 0.5 mM | 3.57 mL | 17.84 mL | 35.68 mL |
| 1 mM | 1.78 mL | 8.92 mL | 17.84 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.57 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1361030-48-9 | 1361030-48-9 供应商 | 1361030-48-9 花费 | 1361030-48-9 生产商 | 订购 1361030-48-9 | 1361030-48-9 代理商