LDC1267

目录号: A13003

TAM Receptor 抑制剂

LDC1267

LDC1267 Chemical Structure

CAS NO. 1361030-48-9

LDC1267是一种高选择性TAM(Tyro3,Axl和Mer)激酶抑制剂,对于Tyro3,Axl和Mer的IC50分别小于5 nM/8 nM/29 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 490.00
10 mg
¥ 770.00
25 mg
¥ 1,540.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

LDC1267是一种高选择性TAM(Tyro3,Axl和Mer)激酶抑制剂,对于Tyro3,Axl和Mer的IC50分别小于5 nM/8 nM/29 nM。
靶点信息
Mer Tyro3 Axl
<5 nM8 nM29 nM
In vitro DMSO Warmed: 89 mg/mL (158.77 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL (3.56 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.84 mL 89.2 mL 178.4 mL
0.5 mM 3.57 mL 17.84 mL 35.68 mL
1 mM 1.78 mL 8.92 mL 17.84 mL
5 mM 0.36 mL 1.78 mL 3.57 mL

*The above data is based on the productmolecular weight 560.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13003
作用机制 Inhibitor (抑制剂)
M. Wt 560.55
Formula C30H26F2N4O5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1361030-48-9
Synonyms LDC 1267, LDC-1267
SMILES CCOC1=CN(N=C1C(=O)NC2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)F)C5=C(C=C(C=C5)F)C

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