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LDK378 (Ceritinib) dihydrochloride

目录号: A15142
ALK 抑制剂
LDK378 二盐酸盐是一种针对 ALK 的强效抑制剂,其 IC50 为0.2 nM,分别对 IGF-1RInsR 显示出40倍和35倍的选择性。
Grouped product items
规格 价格 库存 数量
5mg
¥245.00
现货
10mg
¥350.00
现货
25mg
¥455.00
现货
50mg
¥560.00
现货
100mg
¥840.00
现货
10mM * 1mL in DMSO
¥385.00
现货
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生物活性
Discription LDK378 dihydrochloride is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
产品信息
目录号 A15142
分子式 C28H38Cl3N5O3S
分子量 631.1
CAS号 1380575-43-8
SMILES CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl.Cl.Cl
其他名称 LDK 378 dihydrochloride, LDK-378 dihydrochloride, Ceritinib dihydrochloride
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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