LDN-212854

Name: LDN-212854
SKU: A12821

目录号: A12821

BMP receptor 抑制剂

LDN-212854 Chemical Structure

CAS NO. 1432597-26-6

LDN-212854是一种ALK2偏爱的BMP I型受体激酶抑制剂。

库存：现货

规格	价格	数量
5 mg	￥ 560.00
10 mg	￥ 980.00
25 mg	￥ 1,960.00
50 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 868.00

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生物活性

LDN-212854是一种ALK2偏爱的BMP I型受体激酶抑制剂。

靶点信息

ALK2	ALK1	ALK3	ALK4	ALK5
1.3 nM	2.4 nM	85.8 nM	2133 nM	9276 nM

溶解度 *

In vitro	DMSO	Warmed: 73 mg/mL (179.59 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.6 mL	123 mL	246 mL
0.5 mM	4.92 mL	24.6 mL	49.2 mL
1 mM	2.46 mL	12.3 mL	24.6 mL
5 mM	0.49 mL	2.46 mL	4.92 mL

*The above data is based on the productmolecular weight 406.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12821
作用机制	Inhibitor (抑制剂)
M. Wt	406.5
Formula	C25H22N6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1432597-26-6
Synonyms	LDN212854, LDN 212854
SMILES	C12=C(C3=C4N=CC(C5=CC=C(N6CCNCC6)C=C5)=CN4N=C3)C=CC=C1N=CC=C2