LDN-214117
目录号: A16096
ALK2 抑制剂
LDN-214117 是一种选择性且高效的 ALK2 抑制剂。LDN-214117 主要抑制 ALK2,其生化 IC50 为 24 nM。
Discription | LDN-214117 is a selective and potent ALK2 inhibitor. LDN-214117 inhibited ALK2 most, with a biochemical IC50 of 24 nM. | |||||
---|---|---|---|---|---|---|
Targets |
|
|||||
Cell Research |
|
目录号 | A16096 |
---|---|
分子式 | C25H29N3O3 |
分子量 | 419.52 |
CAS号 | 1627503-67-6 |
SMILES | COC1=C(OC)C(OC)=CC(C2=C(C)N=CC(C3=CC=C(N4CCNCC4)C=C3)=C2)=C1 |
其他名称 | LDN214117, LDN 214117 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 74 mg/mL (176.39 mM) | |
Water | Insoluble | ||
Ethanol | 74 mg/mL (176.39 mM) | ||
In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 2 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.84 mL | 119.18 mL | 238.37 mL |
0.5 mM | 4.77 mL | 23.84 mL | 47.67 mL |
1 mM | 2.38 mL | 11.92 mL | 23.84 mL |
5 mM | 0.48 mL | 2.38 mL | 4.77 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2