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LDN193189 Tetrahydrochloride is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50??500 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.11 mL | 90.53 mL | 181.05 mL |
| 0.5 mM | 3.62 mL | 18.11 mL | 36.21 mL |
| 1 mM | 1.81 mL | 9.05 mL | 18.11 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
*The above data is based on the productmolecular weight 552.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21881 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 552.33 |
| Formula | C25H26Cl4N6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2310134-98-4 |
| Synonyms | LDN 193189, LDN193189 |
| SMILES | C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16.Cl.Cl.Cl.Cl |
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