Lenalidomide (CC-5013)

Name: Lenalidomide (CC-5013)
SKU: A10522
Price: 210 CNY
Rating: 5 (4 reviews)

目录号: A10522

Ubiquitin ligase inducer

4 篇发表文献

Lenalidomide 是一种沙利度胺的衍生物。在体外，lenalidomide 主要具有三种活性：直接的抗肿瘤效果，抑制肿瘤细胞微环境支持，以及免疫调节作用。它通过抑制骨髓基质细胞的支持、抗血管生成效应和抗破骨细胞生成效应，以及免疫调节活性，直接和间接诱导肿瘤细胞凋亡。

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Grouped product items
规格	价格	库存
50mg	¥210.00	现货
100mg	¥280.00	现货
250mg	¥350.00	现货
500mg	¥455.00	现货
1g	¥630.00	现货
5g	¥2,765.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Lenalidomide (CC-5013)发表的4篇文献

Daniel A. Rauch, .et al. , Retrovirology, 2020, 17: 27 PMID: 32859220

A Hayano, .et al. , Int J Clin Oncol, 2019, 1-10 PMID: 30993483

Kumar R, .et al. , Mol Biol Rep, 2018, Oct 11 PMID: 30311125

Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168

生物活性

Discription

Lenalidomide is a derivative of thalidomide. In vitro, lenalidomide has three main activities: direct anti-tumor effect, inhibition of the micro environment support for tumor cells, and immunomodulatory role. It induces tumor cell apoptosis directly and indirectly by inhibition of bone marrow stromal cell support, by anti-angiogenic and anti-osteoclastogenic effects, and by immunomodulatory activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10522
分子式	C13H13N3O3
分子量	259.3
CAS号	191732-72-6
SMILES	C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N
其他名称	Revlimid
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	46 mg/mL (177.43 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+40%PEG 300+5%Tween80+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	38.57 mL	192.83 mL	385.65 mL
0.5 mM	7.71 mL	38.57 mL	77.13 mL
1 mM	3.86 mL	19.28 mL	38.57 mL
5 mM	0.77 mL	3.86 mL	7.71 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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