Lenvatinib mesylate
目录号: A17567
multi-targeted tyrosine kinase inhibitor
Lenvatinib mesylate(E7080 mesylate),一种口服的多靶点酪氨酸激酶抑制剂,能够抑制 VEGFR1-3、FGFR1-4、PDGFR、KIT 和 RET,显示出强大的抗肿瘤活性。
Discription | Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities. | ||
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Targets |
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目录号 | A17567 |
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分子式 | C22H23ClN4O7S |
分子量 | 522.96 |
CAS号 | 857890-39-2 |
SMILES | O=C(C1=C(OC)C=C2N=CC=C(OC3=CC=C(NC(NC4CC4)=O)C(Cl)=C3)C2=C1)N.OS(=O)(C)=O |
其他名称 | E7080 mesylate, E 7080, E-7080 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 34 mg/mL (65.01 mM) | |
Ethanol | <1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.12 mL | 95.61 mL | 191.22 mL |
0.5 mM | 3.82 mL | 19.12 mL | 38.24 mL |
1 mM | 1.91 mL | 9.56 mL | 19.12 mL |
5 mM | 0.38 mL | 1.91 mL | 3.82 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2