Lesinurad
目录号: A12981
SUR inhibitor
Lesinurad 是一种选择性尿酸重吸收抑制剂（SURI），同时也是 URAT1 的选择性抑制剂，URAT1 是肾脏中的一种转运蛋白，负责调节体内尿酸的排泄。
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生物活性
| Discription | Lesinurad is a selective uric acid re-absorption inhibitor (SURI) and is also a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. | |||||
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| Cell Research |
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产品信息
| 目录号 | A12981 |
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| 分子式 | C17H14BrN3O2S |
| 分子量 | 404.28 |
| CAS号 | 878672-00-5 |
| SMILES | C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)O |
| 其他名称 | RDEA594, RDEA 594, RDEA-594 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 72 mg/mL (178.09 mM) | |
| Water | Insoluble | ||
| Ethanol | 49 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.74 mL | 123.68 mL | 247.35 mL |
| 0.5 mM | 4.95 mL | 24.74 mL | 49.47 mL |
| 1 mM | 2.47 mL | 12.37 mL | 24.74 mL |
| 5 mM | 0.49 mL | 2.47 mL | 4.95 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 878672-00-5 | 878672-00-5 供应商 | 878672-00-5 花费 | 878672-00-5 生产商 | 订购 878672-00-5 | 878672-00-5 代理商