产品详情
Lestaurtinib (CEP-701;KT-5555) is a multi-kinase inhibitor with potent activity against the Trk family of receptor tyrosine kinases. Lestaurtinib inhibits JAK2, FLT3 and TrkA with IC50s of 0.9, 3 and less than 25 nM, respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.76 mL | 113.78 mL | 227.55 mL |
0.5 mM | 4.55 mL | 22.76 mL | 45.51 mL |
1 mM | 2.28 mL | 11.38 mL | 22.76 mL |
5 mM | 0.46 mL | 2.28 mL | 4.55 mL |
*The above data is based on the productmolecular weight 439.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A11274 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 439.46 |
Formula | C26H21N3O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 111358-88-4 |
Synonyms | CEP-701, CEP701, CEP701; KT-5555, KT5555, KT 5555 |
SMILES | O=C(NC1)C2=C1C3=C(C4=C52)N(C6=C3C=CC=C6)[C@@]([C@@](O)(CO)C7)(C)O[C@H]7N4C8=C5C=CC=C8 |
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